Immunofluorescence Assay for Serologic Diagnosis of SARS

نویسندگان

  • Paul K. S. Chan
  • King-Cheung Ng
  • Rickjason C. W. Chan
  • Rebecca K. Y. Lam
  • Viola C. Y. Chow
  • Mamie Hui
  • Alan Wu
  • Nelson Lee
  • Florence H.Y. Yap
  • Frankie W. T. Cheng
  • Joseph J. Y. Sung
  • John S. Tam
چکیده

We evaluated an indirect immunofluorescence assay based on virus-infected cells for detecting anti-severe acute respiratory syndrome-associated coronavirus (SARS-CoV) immunoglobulin (Ig) G antibody. All confirmed SARS cases demonstrated seroconversion or fourfold rise in IgG antibody titer; no control was positive. Sensitivity and specificity of this assay were both 100%. Immunofluorescence assay can ascertain the status of SARS-CoV infection.

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عنوان ژورنال:

دوره 10  شماره 

صفحات  -

تاریخ انتشار 2004